[Can the risk of melanoma be calculated?]

The risk of melanoma of the skin may be calculated in two ways: (1) The cumulative total lifetime exposure to sunlight is responsible for LMM in combination with other light-induced skin damages. Xeroderma pigmentosum is the genetic model for this concept. (2) Particularly intense exposure to the sun in early life seems to be a major provocative factor for NM and SSM as well as for the development of melanoma in dysplastic nevus syndrome.