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Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells
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Derivation of Hematopoietic Stem Cells from Murine Embryonic Stem Cells

Published on: February 25, 2007

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Hematopoietic stem cell aging and hematopoietic malignancies.

Eriko Nitta, Atsushi Iwama

    Nihon Rinsho. Japanese Journal of Clinical Medicine
    |December 18, 2018
    PubMed
    Summary

    Aging impairs stem cell function, particularly hematopoietic stem cells (HSCs), through epigenetic dysregulation. These changes are heritable, potentially leading to clonal hematopoiesis and blood diseases in the elderly.

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