Related Experiment Video

Updated: Jan 31, 2026

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool
11:35

The Multiple Sclerosis Performance Test MSPT: An iPad-Based Disability Assessment Tool

Published on: June 30, 2014

58.8K

Prevalence of asthma in multiple sclerosis: A United States population-based study

Eddie Hill1, Hesham Abboud2, Farren B S Briggs3

  • 1Neuroimmunological Disorders Gene-Environment Epidemiology Laboratory, Department of Population and Quantitative Health Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, USA; School of Medicine, Case Western Reserve University, Cleveland, OH, USA.

Multiple Sclerosis and Related Disorders
|December 18, 2018
PubMed
Abstract

Insights

Asthma is significantly more common in multiple sclerosis (MS) patients than the general population, especially in younger and older adults. This highlights the need for integrated care strategies for MS comorbidities.

Area of Science:

  • Neurology
  • Pulmonology
  • Epidemiology

Background:

  • Multiple sclerosis (MS) and asthma are debilitating multifactorial diseases impacting daily life.
  • The prevalence of asthma in individuals with MS is not well-established.
  • Understanding this comorbidity is crucial for comprehensive patient care.

Purpose of the Study:

  • To determine the prevalence of asthma in a large cohort of patients with multiple sclerosis (MS).
  • To analyze asthma prevalence in MS patients considering age, gender, and race.
  • To compare asthma rates in MS patients versus the general population.

Main Methods:

  • A U.S. population-based, cross-sectional study utilizing electronic health records from 56.6 million individuals.
  • Evaluated asthma prevalence in 141,880 MS patients and 56,416,790 non-MS individuals.
  • Stratified analyses by age, gender, and race (White Americans, African Americans).

Main Results:

  • Asthma prevalence was significantly higher in the MS cohort compared to the general population across all demographics.
  • After adjusting for age and gender, asthma was three times more common in MS patients.
  • MS patients exhibited a U-shaped asthma prevalence by age (highest in <30 and ≥80 years), unlike the non-MS cohort.

Conclusions:

  • Asthma is substantially more prevalent in individuals with MS, particularly the young and elderly.
  • These findings underscore the importance of managing comorbidities in comprehensive MS care.
  • The increased asthma prevalence in MS warrants further investigation into underlying mechanisms and integrated treatment approaches.
Keywords:
AsthmaComorbidityMultiple sclerosisPrevalence

More Related Videos

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis09:41

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

12.0K
A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS08:18

A Protocol for the Use of Remotely-Supervised Transcranial Direct Current Stimulation tDCS in Multiple Sclerosis MS

Published on: December 26, 2015

18.1K

Related Concept Videos

Prevalence and Incidence01:08

Prevalence and Incidence

In statistical epidemiology and health sciences, two essential metrics—prevalence and incidence—are fundamental for understanding disease dynamics within a population. These measures enable public health officials, epidemiologists, and researchers to assess the burden of diseases, allocate resources effectively, and design impactful public health policies and interventions.
Prevalence indicates the proportion of individuals in a population who have a specific disease or health...
1.8K
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
3.5K
Measurement: Derived Units03:02

Measurement: Derived Units

The International System of Units or SI system, by international agreement, has fixed measurement units for seven fundamental properties: length, mass, time, temperature, electric current, amount of substance, and luminosity. These are called the SI base units.
55.4K
Measurement: Standard Units03:38

Measurement: Standard Units

Every measurement provides three kinds of information: the size or magnitude of the measurement (a number), a standard of comparison for the measurement (a unit), and an indication of the uncertainty of the measurement. While the number and unit are explicitly represented when a quantity is written, the uncertainty is an aspect of the errors in the measurement results.
79.8K
What is Population Genetics?01:25

What is Population Genetics?

A population is composed of members of the same species that simultaneously live and interact in the same area. When individuals in a population breed, they pass down their genes to their offspring. Many of these genes are polymorphic, meaning that they occur in multiple variants. Such variations of a gene are referred to as alleles. The collective set of all the alleles within a population is known as the gene pool.
64.7K
Bioavailability Study Design: Single Versus Multiple Dose Studies01:11

Bioavailability Study Design: Single Versus Multiple Dose Studies

Bioavailability studies are essential for understanding how a drug is absorbed, distributed, metabolized, and excreted in the body. These studies assess the extent and rate at which the active pharmaceutical agent becomes available at the site of action. The design of bioavailability studies can involve single-dose or multiple-dose regimens, each with distinct advantages and limitations.Single-dose studies are the preferred approach due to their simplicity and reduced drug exposure for...
238