Related Experiment Video
Updated: Jan 31, 2026

Meta-Analysis of the Effectiveness and Safety of Shugan Jieyu Capsules for the Treatment of Insomnia
Published on: February 17, 2023
Chinese herbal medicine for recurrent aphthous stomatitis: a protocol for systematic review and meta-analysis
Ying Zhang1, Kwan-Him Ng2, Chih-Yu Kuo3
1Department of Geriatrics, the Third Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou, China.
Background:
Recurrent aphthous stomatitis (RAS) is the most frequent form of oral ulceration, characterized by recurrent oral mucosal ulceration in an otherwise healthy individual. This study was designed to evaluate the efficacy and safety of Chinese herbal medicine for recurrent aphthous stomatitis.
Methods:
Five databases will be searched from inception to date, including PubMed, Cochrane Library, EMBASE,CNKI, and CBM. The researchers will comprehensively screen clinical randomized trials of Chinese herbal medicine for recurrent aphthous stomatitis. The review will be conducted by 2 independent authors without time and language limitation. The risk of bias will be assessed by the Cochrane risk of bias tool.
Results:
Ethical approval is not required because this study is based on published papers. After peer-review, the study will be disseminated in scientific journals and conferences.
Conclusion:
This systematic review will provide evidence for the efficacy and safety of Chinese medicine for recurrent aphthous stomatitis.
Prospero Registration:
CRD42018111955.
Related Concept Videos
Review and Preview
Percentiles are a type of fractile that partition data into...
Review and Preview
Random and Systematic Errors
Directing Effect of Substituents: meta-Directing Groups
Systematic Sampling Method
Systematic sampling is one of the simplest methods...
Propagation of Uncertainty from Systematic Error

