Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Learning RuBisCO's birth and subsequent environmental adaptation.

Hiroki Ashida1, Eiichi Mizohata2,3, Akiho Yokota4

  • 1Graduate School of Human Development and Environment, Kobe University, Tsurukabuto, Kobe City 657-8501, Japan.

Biochemical Society Transactions
|December 19, 2018
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transient molecular chimerism for exploiting xenogeneic organelles.

Nature communications·2026
Same author

Real-time capture of domain movements during copper amine oxidase catalysis by mix-and-inject serial crystallography.

Nature communications·2025
Same author

Hydrated ionic liquids enhance stability and preserve functionality in transmembrane proteins.

International journal of biological macromolecules·2025
Same author

Tracking Protein Motions using Serial Femtosecond Crystallography with X-Ray Free-Electron Laser.

Current protocols·2025
Same author

Enhanced Production of Rebaudioside D and Rebaudioside M through V155T Substitution in the Glycosyltransferase UGT91D2 from <i>Stevia rebaudiana</i>.

Journal of agricultural and food chemistry·2025
Same author

Metabolic analysis reveals the contribution of mechanosensitive channel MscM to extracellular release of glutamate in glycogen-deficient Synechococcus elongatus.

Journal of bioscience and bioengineering·2024

The enzyme RuBisCO evolved from early life, adapting its structure and function over 4 billion years to become central to photosynthesis and CO2 fixation in response to changing atmospheric conditions.

Area of Science:

  • Biochemistry
  • Evolutionary Biology
  • Molecular Biology

Background:

  • Early life utilized limited genes, with evolution driven by replication, mutation, and DNA exchange.
  • The enzyme RuBisCO (ribulose 1,5-bisphosphate carboxylase/oxygenase) originated in primitive archaea.
  • Atmospheric CO2 and O2 levels fluctuated significantly over Earth's history.

Purpose of the Study:

  • To review the evolutionary adaptation of RuBisCO.
  • To explore how RuBisCO specialized for CO2 fixation.
  • To examine the functional and structural changes in RuBisCO over time.

Main Methods:

  • Literature review of RuBisCO evolution.
  • Analysis of structural and functional adaptations.
  • Examination of historical environmental changes.
Keywords:
RuBisCoRuBisCo activaseenvironmental adaptationmethanogenic archaearelative specificity

Related Experiment Videos

Main Results:

  • RuBisCO's origins trace back to methanogenic archaea.
  • The enzyme has undergone significant evolution in response to environmental shifts.
  • Adaptations in structure and function enabled RuBisCO to become a key CO2-fixing enzyme.

Conclusions:

  • RuBisCO's evolutionary journey highlights its critical role in Earth's carbon cycle.
  • Structural and functional changes underscore its adaptation to diverse environmental pressures.
  • Understanding RuBisCO evolution provides insights into ancient biochemistry and photosynthesis.