Effect of Course Structure on the Accuracy of Nonsterile Compounded Preparations
Koo Yeon Yoo1, Robert P Shrewsbury1
1Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, North Carolina.
American Journal of Pharmaceutical Education
|December 19, 2018
Summary
Students in the new pharmacy curriculum (TC) showed similar compounding skills to the legacy curriculum (PCL) in some preparations. However, the hydrocortisone medication stick demonstrated a need for enhanced understanding of preparation science.
Area of Science:
- Pharmaceutical Sciences
- Pharmacy Education
Background:
- Pharmacy curricula evolve to meet changing educational needs.
- Assessing student competency in pharmaceutical compounding is crucial for patient safety.
Purpose of the Study:
- To compare the compounding competency of students under a new curriculum (TC) versus a legacy curriculum (PCL).
- To evaluate if the transformed curriculum (TC) adequately prepares students in pharmaceutical compounding.
Main Methods:
- Students from both legacy (PCL) and transformed (TC) curricula compounded four identical nonsterile preparations.
- Compounding competency was assessed using relative potency and weight variation metrics.
- Preparations represented a range of compounding complexities.
Main Results:
- Mean relative potencies differed significantly for three preparations; only the TC hydrocortisone stick fell outside acceptable limits.
- Standard deviations varied greatly, suggesting differences in first-attempt success rates.
- Weight variation data for troches and tablet triturates were nearly identical between groups.
Conclusions:
- Equivalent compounding competency is achievable for simple preparations like solutions or those using fixed molds.
- The hydrocortisone medication stick results indicate that complex preparations may require deeper scientific understanding or more instructional time.
- Curriculum transformation requires careful evaluation of competency in all areas of pharmaceutical compounding.
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