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Updated: Jan 31, 2026

Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus MRSA
Published on: February 9, 2011
Postoperation of preauricular fistula cellulitis caused by methicillin-resistant staphylococcus aureus infection
1Department of Otolaryngology-Head and Neck Surgery, Lanzhou General Hospital of People's Liberation Army, Gansu Province, PR China.
Abstract:
A one-year-old baby girl with one-month history of recurrent pus fluid exuding from her left preauricular sinus orifice, who failed multiple courses of surgical drainage of the abscess and persistent debridement for the wound, presented with MRSA infection. The patient was treated with linezolid for three days. Her pain and paresthesia resolved, and C-reactive protein decreased to normal.
Insights
A pediatric MRSA infection of a preauricular sinus in an infant was successfully treated with linezolid. This antibiotic therapy resolved pain and paresthesia, indicating effective treatment for the resistant bacterial infection.
Area of Science:
- Pediatric Infectious Diseases
- Dermatology
- Microbiology
Background:
- Preauricular sinus infections can be recurrent and challenging to treat.
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant threat in pediatric infections.
- Previous surgical interventions failed to resolve the infant's persistent infection.
Purpose of the Study:
- To report a case of successful linezolid treatment for a complicated preauricular sinus infection caused by MRSA in an infant.
- To highlight the efficacy of linezolid in managing resistant bacterial infections in pediatric patients.
Main Methods:
- A one-year-old female infant with a month-long history of recurrent pus discharge from a preauricular sinus was diagnosed with MRSA infection.
- The patient received a three-day course of linezolid.
- Clinical symptoms and inflammatory markers were monitored.
Main Results:
- Following linezolid treatment, the infant's pain and paresthesia resolved.
- C-reactive protein levels normalized, indicating resolution of the infection.
- The preauricular sinus infection showed a positive response to the antibiotic therapy.
Conclusions:
- Linezolid is an effective treatment option for MRSA infections of the preauricular sinus in infants.
- Early and appropriate antibiotic selection is crucial for managing complex pediatric infections.
- This case underscores the importance of considering advanced antibiotic therapies for refractory infections.
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