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Updated: Jan 31, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
Published on: May 23, 2021
Analysis of infectious spondylodiscitis: 7-years data
Gulay Okay1, Yasemin Akkoyunlu2, Sibel Bolukcu3
1Gulay Okay, MD. Department of Infectious Diseases and Clinical Microbiology, Bezmialem Vakif University, Istanbul, Turkey.
Pyogenic spondylodiscitis (SD) is the most common form of this rare spinal infection. Leucocytosis indicates pyogenic SD, while thoracic involvement and night sweats suggest tuberculous SD.
Area of Science:
- Infectious Diseases
- Spinal Infections
- Diagnostic Medicine
Background:
- Infectious spondylodiscitis (SD) presents with non-specific symptoms, complicating diagnosis.
- Understanding the distinct clinical and diagnostic features of different SD types is crucial for effective management.
Purpose of the Study:
- To delineate the clinical and diagnostic characteristics of infectious spondylodiscitis.
- To differentiate between pyogenic, tuberculous, and brucellar forms of SD based on patient data.
Main Methods:
- Retrospective analysis of 118 patients diagnosed with SD between 2011 and 2017.
- Categorization of SD into pyogenic, tuberculous, and brucellar types.
- Collection and analysis of clinical, laboratory, and microbiological data.
Main Results:
- Pyogenic SD (PSD) was most frequent (68.6%), associated with higher leucocytosis (p=0.01).
- Tuberculous SD (TSD) commonly involved the thoracic spine (47.6%) and presented with paravertebral abscesses (42.8%).
- Brucellar SD (BSD) showed higher prevalence of sacral involvement (12.5%). Female gender, thoracic involvement, and night sweats predicted TSD.
Conclusions:
- PSD is the most common SD type, with leucocytosis as a key indicator.
- TSD is characterized by thoracic involvement and paraspinal abscesses; female gender and night sweats are predictive markers.
- BSD predominantly affects the sacral region. Surgical specimens yield higher culture positivity than FNAB.
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