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Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...
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Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
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Focus on improved patient management

Katerina Rusinova1, Michael Darmon2,3,4

  • 1Department of Anesthesiology and Intensive Care Medicine, First Faculty of Medicine, Charles University, Prague, Czech Republic. katerina.rusinova@vfn.cz.

Intensive Care Medicine
|December 19, 2018
PubMed
Summary

No abstract available in PubMed .

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