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Updated: Jan 31, 2026

Standardized Technique of Aortic Valve Re-implantation for Valve-sparing Aortic Root Replacement
Published on: December 11, 2017
TAVI as Therapy of Choice for Aortic Valve Disease in Osteogenesis Imperfecta
Jan-Philipp Minol1, Tobias Zeus2, Alexander Blehm3
1Department of Cardiovascular Surgery, University Hospital, Düsseldorf, Germany. Electronic correspondence: phil.minol@gmx.de.
Abstract:
Osteogenesis imperfecta (OI) is a syndrome that is often associated with dysfunction of the aortic valve. Because of the resultant fragile vessels and impaired hemostasis, surgical therapy to treat OI is challenging. Previous reports have suggested that transcatheter aortic valve implantation (TAVI) might be a suitable treatment for this condition. To the best of the authors' knowledge, the present case is the first to describe a young patient who underwent successful TAVI to treat osteogenesis imperfecta. The proposal of transfemoral TAVI serving as first-line therapy for aortic valve stenosis in patients suffering from osteogenesis imperfect was confirmed.
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