Related Experiment Video
Updated: Jan 31, 2026

A Tripeptide-Stabilized Nanoemulsion of Oleic Acid
Published on: February 27, 2019
The prevention effects of cryptotanshinone nanoemulsion on postoperative peritoneal adhesions
Wang Chengxi1, Guo Rishuo1, Gu QuLiang2
1a School of Pharmacy, Guangdong Pharmaceutical University , Guangzhou , China.
Abstract:
The purpose of this study was to prepare a novel cryptotanshinone-loaded nanoemulsion (Cry LN) and to evaluate its prevention effect on the postoperative peritoneal adhesions (PPA). The Cry LN was prepared by high-pressure homogenization method, and various methods were used to investigate the physicochemical properties. The results showed that Cry LN has nanoscale particle size with uniform distribution and could slowly release the incorporated drug compared with Cry solution. With superior safety, Cry LN could increase the ratio of tissue plasminogen activator (tPA)/plasminogen activator inhibitor-1 (PAI-1) up to 673% compared with control group. Furthermore, in vivo animal study confirmed the Cry LN activated the fibrinolytic system and successfully prevented PPA formation in rat. In conclusion, Cry nanoemulsion could be considered as a potentially promising and effective strategy for PPA treatment.
More Related Videos
10:35Assessment of Antibody-based Drugs Effects on Murine Bone Marrow and Peritoneal Macrophage Activation
Published on: December 26, 2017
07:32Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection
Published on: September 1, 2023
Related Concept Videos
Adhesion
Capillary action is a result of water’s adhesive tendencies. When a narrow...
Cancer Prevention
Some...
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Prevention of Further Absorption of Poison
Preventive Healthcare Services
Peritoneal Dialysis I: Introduction and Procedure