Related Experiment Video
Updated: Jan 31, 2026
Quantitating Iron Transport Across the Mouse Placenta In Vivo Using Nonradioactive Iron Isotopes
Published on: May 10, 2022
Nickel-Iron Dithiolato Hydrides Derived from H2 Activation by Their μ-Hydroxo Ligand-Containing Analogues
Li-Cheng Song1,2, Xi-Yue Yang1, Xiu-Yun Gao1
1Department of Chemistry, State Key Laboratory of Elemento-Organic Chemistry, College of Chemistry , Nankai University , Tianjin 300071 , China.
Abstract:
Here, we describe the synthesis and characterization of the two μ-hydrido models of [NiFe]H2ases prepared from a new type of H2 activation by the corresponding two μ-hydroxo models. In addition, another μ-hydrido model prepared by the anionic exchange between one of the two μ-hydrido models and KPF6 is also reported. Interestingly, the synthesis of the two μ-hydrido models from H2 activation represents the first functional modeling of the H2 activation catalyzed by the [NiFe]H2ase (Ni-SIr)I state to give the Ni-R state.
Related Concept Videos
00:49Ligand Binding and Linkage
00:49Ligand Binding and Linkage
02:40Ligand Binding Sites
Protein-ligand interactions are quite specific; even though numerous potential ligands surround a cellular protein at any given time, only a particular ligand can bind to that protein. Moreover, a ligand binds only to a dedicated area on the surface of the protein, known as the...
02:40Ligand Binding Sites
02:51Metal-Ligand Bonds
In these complexes, transition metals form coordinate covalent bonds, a kind of Lewis acid-base interaction in which both of the electrons in the bond are contributed by a donor (Lewis base) to an electron acceptor (Lewis acid). The Lewis acid in...
01:17Esters to Alcohols: Hydride Reductions
Lithium aluminum hydride is a source of hydride ions and functions as a nucleophile. The mechanism proceeds in three steps. Firstly, the nucleophilic hydride ion attacks the carbonyl carbon of the ester to form a tetrahedral intermediate. Subsequently, the carbonyl group re-forms,...