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Related Experiment Videos

Carcinoid tumor in Meckel's diverticulum.

Y N Silk1, H O Douglass, R Penetrante

  • 1Department of Surgical Oncology, Roswell Park Memorial Institute, Buffalo, New York 14263.

The American Surgeon
|November 1, 1988
PubMed
Summary

Carcinoid tumors in Meckel

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Pathology

Background:

  • Meckel's diverticulum is a congenital anomaly of the small intestine.
  • Carcinoid tumors are neuroendocrine neoplasms that can arise in various locations, including the gastrointestinal tract.

Observation:

  • Carcinoid tumors originating in Meckel's diverticulum are exceptionally rare, with limited documented cases.
  • These tumors are frequently discovered incidentally during autopsies or unrelated surgical procedures.
  • In approximately one-third of instances, these tumors manifest symptomatically, necessitating surgical intervention.

Findings:

  • Preoperative diagnosis of carcinoid tumor in Meckel's diverticulum is challenging and often not apparent until post-surgical specimen examination.
  • Surgical resection of the affected intestinal segment and its mesentery typically leads to a cure.
  • Despite curative resection, the potential for metastatic disease and carcinoid syndrome persists.

Implications:

  • Considering rare conditions like Meckel's diverticulum carcinoid tumors can aid in accurate preoperative diagnosis when clinical signs and symptoms are atypical.
  • Patients with carcinoid of Meckel's diverticulum have an increased incidence of second primary malignancies.
  • Early recognition and appropriate surgical management are crucial for favorable outcomes, though long-term surveillance for metastasis and secondary cancers is warranted.

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