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Relationship between Helicobacter pylori infection and GERD
Serena Scida1, Michele Russo, Chiara Miraglia
1Dipartimento di Medicina e Chirurgia, Università degli Studi di Parma. scidaserena@gmail.com.
Acta Bio-Medica : Atenei Parmensis
|December 19, 2018
Summary
The link between gastroesophageal reflux disease (GERD) and Helicobacter pylori (H. pylori) infection remains unclear. This review examines current literature to understand their complex relationship.
Area of Science:
- Gastroenterology
- Microbiology
Background:
- Gastroesophageal reflux disease (GERD) involves chronic esophageal exposure to stomach acid.
- Helicobacter pylori (H. pylori) infection is linked to peptic ulcers, gastritis, and gastric cancer.
- The connection between GERD and H. pylori infection is a subject of ongoing scientific debate.
Purpose of the Study:
- To review recent literature on the relationship between GERD and H. pylori infection.
- To synthesize current data regarding the potential causal links or associations.
Main Methods:
- Literature search conducted on PubMed and Google Scholar.
- Keywords used included: gastroesophageal reflux disease, Helicobacter pylori, acid-related disorders, GERD, and esophagitis.
Main Results:
- No definitive causal relationship between GERD and H. pylori infection has been established in the literature.
- Some studies suggest esophagitis may develop after H. pylori infection is eradicated.
Conclusions:
- The interplay between GERD and H. pylori infection requires further investigation.
- Understanding this relationship is crucial for managing acid-related and H. pylori-associated gastrointestinal disorders.
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