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Updated: Jan 31, 2026

Murine Endoscopy for In Vivo Multimodal Imaging of Carcinogenesis and Assessment of Intestinal Wound Healing and Inflammation
Published on: August 26, 2014
Endoscopy - esophagography
Abstract:
Endoscpy is an essential tool in the diagnosis of gastroesophageal reflux disease (GERD) including reflux esophagitis. The Los Angeles (LA) classification was introduced in 1994 to provide endoscopists with a grading system(A-D) to describe and classify the appearance of erosive changes and mucosal breaks in the distal esophagus. Recent imaging techniques such as mucosal staining, magnification, and high-definition(high-resolution) endoscopy and electronic chromoendoscopy have improved the ability to visualize the superficial mucosa of the esophagus. Double-contrast esophagogram have sensitivity approaching 90 % for the diagnosis of reflux esophagitis because of the ability to detect superficial ulcers or other findings that cannot be visualized on single-contrast studies.

