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Chronic pharyngitis and laryngitis caused by gastroesophageal reflux
Nihon Rinsho. Japanese Journal of Clinical Medicine
|December 19, 2018
Summary
Proton pump inhibitors (PPIs) effectively reduce reflux-induced laryngopharyngeal symptoms. However, the PPI test is not yet a reliable diagnostic tool for determining if GER causes chronic throat and voice issues.
Area of Science:
- Gastroenterology
- Otolaryngology
Background:
- Gastroesophageal reflux disease (GERD) can manifest as laryngopharyngeal symptoms (LPS) like hoarseness and cough.
- A significant portion of GERD patients experience these throat-related symptoms.
Purpose of the Study:
- To evaluate the efficacy of proton pump inhibitors (PPIs) in treating GERD-related laryngopharyngeal symptoms.
- To assess the diagnostic utility of the PPI test for GERD-induced chronic pharyngitis and laryngitis.
Main Methods:
- An updated meta-analysis was conducted.
- Included patients with suspected GER-induced laryngopharyngeal symptoms.
Main Results:
- Proton pump inhibitors (PPIs) demonstrated a significant reduction in laryngopharyngeal symptoms compared to placebo.
- The effectiveness of the PPI test as a diagnostic tool for this patient group remains uncertain.
Conclusions:
- PPIs are effective in managing reflux-induced laryngopharyngeal symptoms.
- A definitive diagnostic tool is lacking to confirm GER as the cause of chronic pharyngitis and laryngitis.
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