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Updated: Jan 31, 2026
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Spatio-Temporal In Vivo Imaging of Ocular Drug Delivery Systems using Fiberoptic Confocal Laser Microendoscopy
Published on: September 27, 2021
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Modified cells as potential ocular drug delivery systems.
Tatiana Tennikova1, Arto Urtti2
1Institute of Chemistry, Saint-Petersburg State University, Sankt-Peterburg, Russian Federation.
Drug Discovery Today
|December 19, 2018
Summary
Cell technologies offer promising solutions for targeted ocular drug delivery, enabling prolonged drug action and minimally invasive treatments for retinal diseases. Further research is needed to explore their full potential in this specialized area.
Area of Science:
- Biomedical Engineering
- Ophthalmology
- Cellular Therapeutics
Background:
- Ocular drug delivery faces significant challenges, particularly for treating retinal diseases.
- Current methods often lack targeted delivery, sustained drug action, and are minimally invasive.
- Advanced therapeutic strategies are required to overcome these limitations.
Purpose of the Study:
- To review cell technologies for ocular drug delivery.
- To highlight the potential of genetically engineered and non-genetically modified cells.
- To discuss the application of these cell-based approaches in the ocular context.
Main Methods:
- Review of existing literature on cell technologies for drug delivery.
- Analysis of genetic and non-genetic cell modification strategies.
- Focus on the adaptation and application of these technologies for ocular targets.
Main Results:
- Cell technologies inherently offer targeted delivery, prolonged drug action, and minimally invasive administration.
- These principles are theoretically applicable to ocular drug delivery challenges.
- Current studies exploring cell technologies for ocular delivery are limited but show promise.
Conclusions:
- Cell-based drug delivery systems hold significant potential for advancing ocular therapeutics.
- Further investigation and development are crucial to fully realize their benefits in treating eye diseases.
- These technologies represent a promising frontier in minimally invasive, targeted ocular treatments.
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