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SugarSketcher: Quick and Intuitive Online Glycan Drawing
Davide Alocci1,2, Pavla Suchánková3,4, Renaud Costa5
1Proteome Informatics Group, SIB Swiss Institute of Bioinformatics, 1211 Geneva, Switzerland. davide.alocci@sib.swiss.
Molecules (Basel, Switzerland)
|December 20, 2018
Summary
SugarSketcher is a new JavaScript tool for easily drawing and exporting complex glycan structures using Symbol Nomenclature for Glycans (SNFG) notation. This intuitive module aids both experts and beginners in glycoinformatics research.
Area of Science:
- Glycomics
- Bioinformatics
- Computational Chemistry
Background:
- Accurate representation of complex carbohydrate structures is crucial for understanding biological processes.
- Existing tools for glycan drawing may lack user-friendliness or integration capabilities.
Purpose of the Study:
- To develop an intuitive and fast JavaScript module for drawing glycans.
- To enable export of glycan structures in common formats like GlycoCT and image formats (SVG).
- To facilitate integration into web-based glycoinformatics projects.
Main Methods:
- Developed a JavaScript interface module, SugarSketcher.
- Implemented Symbol Nomenclature for Glycans (SNFG) for structure drawing.
- Included a "quick mode" for beginners and a "normal mode" with advanced options for experts.
- Ensured no backend server or browser plugins are required for integration.
Main Results:
- SugarSketcher provides an intuitive and fast interface for glycan structure drawing.
- The module supports export to GlycoCT for sequence encoding and SVG for image representation.
- It is easily integrable into existing web glycoinformatics platforms.
- Offers distinct modes catering to both novice and expert users.
Conclusions:
- SugarSketcher offers a versatile and accessible solution for glycan structure visualization and data exchange.
- Its ease of integration and dual-mode functionality enhance its utility in glycoinformatics.
- Encourages community contribution to its open-source development.
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