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Construction of Lambda-Cyhalothrin Nano-Delivery System with a High Loading Content and Controlled-Release Property.
Yue Shen1, Huaxin Zhu2, Jianxia Cui3
1Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Beijing 100081, China. shenyue@caas.cn.
Nanomaterials (Basel, Switzerland)
|December 20, 2018
Summary
This study developed a novel nano-delivery system using polylactic acid (PLA) to encapsulate lambda-cyhalothrin (LC) pesticides. The new formulation significantly improves pesticide adhesion to foliage, enhancing utilization and reducing environmental impact.
Area of Science:
- Agricultural Chemistry
- Materials Science
- Nanotechnology
Background:
- Traditional pesticide formulations suffer from poor dispersibility, foliar adhesion, and high organic solvent use, leading to low efficacy and environmental pollution.
- Developing advanced delivery systems is crucial for improving pesticide utilization and sustainability in agriculture.
Purpose of the Study:
- To create a lambda-cyhalothrin (LC)-loaded nano-delivery system using polylactic acid (PLA) to enhance foliar retention and release.
- To investigate the impact of formulation parameters on nanoparticle characteristics and pesticide loading.
- To evaluate the foliar adhesion and release properties of the developed nano-delivery system compared to commercial formulations.
Main Methods:
- Utilized a solvent evaporation method to synthesize polylactic acid (PLA) nanoparticles encapsulating lambda-cyhalothrin (LC).
- Optimized nanoparticle characteristics (size, loading, encapsulation efficiency) by adjusting stabilizer concentration, water-oil ratio, and carrier content.
- Analyzed nanoparticle morphology, size, and surface properties using relevant characterization techniques.
- Assessed sustained release profiles and foliar adhesion properties of the LC/PLA nano-delivery system.
Main Results:
- Synthesized uniform, spherical LC/PLA nanoparticles with sizes under 200 nm and high encapsulation efficiency (>90%).
- Achieved a high LC loading capacity of up to 46.6 wt.%, significantly influenced by formulation parameters.
- Demonstrated significantly enhanced foliar adhesion of the nano-delivery system compared to commercial formulations due to reduced surface tension and contact angle.
- Observed distinct sustained release behaviors dependent on LC loading within the nanoparticles.
Conclusions:
- The developed LC/PLA nano-delivery system offers a promising alternative to traditional pesticide formulations.
- Improved foliar adhesion and sustained release characteristics of the nano-delivery system can substantially increase pesticide utilization efficiency.
- This nanotechnology approach contributes to reducing environmental pollution associated with pesticide application.
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