Systematic preoperative CT scan is associated with reduced risk of stroke in minimally invasive mitral valve surgery:

Jeremy R Leonard1, Matthew Henry1, Mohamed Rahouma1

  • 1Department of Cardiothoracic Surgery, Weill Cornell Medicine, New York City, NY, USA.

Abstract

Insights

Systematic pre-operative CT screening before minimally invasive mitral valve surgery significantly reduces stroke and dialysis risks. This approach also shows a trend toward lower operative mortality, improving patient outcomes.

Area of Science:

  • Cardiovascular Surgery
  • Medical Imaging
  • Health Outcomes Research

Background:

  • Minimally invasive mitral valve surgery (MIMVS) is increasingly common.
  • Patients undergoing MIMVS face elevated perioperative stroke risk, often from retrograde aortic embolization during femoral cardiopulmonary bypass.
  • Pre-operative computed tomography (CT) screening aids in visualizing the aorta and femoro-iliac vessels, enabling personalized surgical planning.

Purpose of the Study:

  • To determine if systematic pre-operative CT screening reduces post-operative stroke incidence in MIMVS.
  • To assess the impact of CT screening on other complications, including operative mortality and renal failure.

Main Methods:

  • A meta-analysis of studies published in PubMed (inception-May 2018) was conducted.
  • Studies involving MIMVS with retrograde arterial perfusion were categorized into systematic pre-operative CT screening (CT-group) and no CT screening (Non-CT) groups.
  • Pooled event rates for operative mortality, post-operative stroke, myocardial infarction, and new-onset renal failure requiring dialysis were calculated and compared between groups.

Main Results:

  • Analysis of 57 studies (13,731 patients) revealed a significantly lower post-operative stroke rate in the CT-group (1.5%) compared to the Non-CT group (2.2%; P=0.03).
  • The incidence of new dialysis requirement was also significantly lower in the CT-group (0.8% vs. 2.3%; P=0.02).
  • Operative mortality was 1.4% overall, with a trend towards better outcomes in the CT-group (0.8% vs. 1.6%; P=0.05).

Conclusions:

  • Systematic pre-operative CT screening is associated with a reduced risk of post-operative stroke after MIMVS.
  • CT screening also correlates with a lower need for dialysis and a trend toward decreased operative mortality.
  • These findings support the utility of pre-operative CT screening for optimizing patient safety in MIMVS.

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