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MHE Testing in Real World Scenario.

Mette M Lauridsen1, Hendrik Vilstrup2

  • 1Department of Gastroenterology and Hepatology, Hospital of South West Jutland, Finsensgade 35, 6700 Esbjerg, Denmark.

Journal of Clinical and Experimental Hepatology
|December 20, 2018
PubMed
Summary
This summary is machine-generated.

Healthcare professionals know about minimal hepatic encephalopathy (MHE), but hesitate to use psychometric testing. This review addresses doubts about testing and treatment benefits for MHE patients.

Keywords:
CFF, Critical Flicker Frequency TestCRT, Continuous Reaction Time TestEEG, Electro EncephalographyICT, Inhibitory Control Task TestMHE, Minimal Hepatic EncephalopathyPHES, Portosystemic Hepatic Encephalopathy ScoreTIPS, Transhepatic Intrajugular Portosystemic Shuntcovertdiagnostic testencephalopathyminimalpsychometry

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Area of Science:

  • Hepatology
  • Neurology
  • Psychometrics

Background:

  • Minimal hepatic encephalopathy (MHE) awareness is high among professionals.
  • Psychometric testing for MHE is underutilized in clinical practice, offered only to select cirrhosis patients.

Purpose of the Study:

  • To address professional hesitation regarding MHE psychometric testing.
  • To clarify the benefits of anti-MHE treatment and the utility of psychometric tests in identifying suitable candidates.

Main Methods:

  • This mini-review synthesizes current knowledge on MHE psychometric testing.
  • It examines the efficacy of available anti-MHE treatments.

Main Results:

  • Hesitation stems from uncertainty about appropriate tests and treatment benefits.
  • Lack of confidence in identifying patients who will benefit from anti-MHE treatment is a key barrier.

Conclusions:

  • The majority of MHE patients are not receiving efficient anti-MHE treatment due to testing uncertainties.
  • This review aims to resolve doubts and encourage wider adoption of MHE psychometric testing and treatment.