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Radiological Intervention for Shunt Related Encephalopathy
Silvia Nardelli1, Stefania Gioia1, Lorenzo Ridola2
1Department of Clinical Medicine, Centre for the Diagnosis and Treatment of Portal Hypertension, "Sapienza" University of Rome, Rome, Italy.
Journal of Clinical and Experimental Hepatology
|December 20, 2018
Summary
Hepatic encephalopathy (HE) in cirrhosis patients can stem from liver failure or shunts. Radiological procedures like TIPS reduction or shunt occlusion effectively treat refractory HE by addressing these shunts.
Area of Science:
- Hepatology
- Neurology
- Radiology
Background:
- Hepatic encephalopathy (HE) affects up to 30% of cirrhosis patients.
- HE can result from liver failure or portal-systemic shunting.
- Chronic HE may be linked to spontaneous or radiological shunts.
Purpose of the Study:
- To investigate the role of portal-systemic shunts in HE development.
- To evaluate the efficacy of radiological procedures for refractory HE.
Main Methods:
- Review of clinical and pathophysiologic observations.
- Analysis of radiological procedures such as Transjugular Intrahepatic Portosystemic Shunt (TIPS) reduction and shunt occlusion.
Main Results:
- Portal-systemic shunts are significant in HE development.
- TIPS reduction and shunt occlusion are safe and effective radiological treatments.
- These procedures can ameliorate neurological symptoms in refractory HE patients.
Conclusions:
- Portal-systemic shunts play a crucial role in hepatic encephalopathy.
- Radiological interventions targeting shunts offer a viable treatment for refractory HE.
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