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Guidelines and Experience Using Imaging Biomarker Explorer (IBEX) for Radiomics

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Centralized Clinical Trial Imaging Data Management: Practical Guidance from a Comprehensive Cancer Center's

Brandon Lee¹, A Abbott², S Davidson³

¹Department of Imaging and Center for Biomedical Imaging in Oncology, Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA, 02215, USA. Brandon_Lee1@dfci.harvard.edu.

Journal of Digital Imaging

|December 20, 2018

Summary

Properly managed medical imaging data is crucial for accurate clinical trial results. Centralized data management ensures quality, consistency, and timely delivery of imaging data to sponsors.

Keywords:

Clinical trial and imaging data management Imaging de-identification Quality improvement Relational database Web form Workflow

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Area of Science:

Clinical research
Medical imaging analysis
Data management in healthcare

Background:

Medical imaging is essential for clinical trials, requiring meticulous management for accurate and timely data delivery.
Standardized workflows are critical for high-quality clinical trial data management, minimizing protocol deviations and data transfer delays.

Purpose of the Study:

To describe the practical implementation of a centralized clinical trial imaging data management process.
To prevent task fragmentation across multiple research centers and staff.
To ensure the delivery of quality, accurate, and timely imaging data to clinical trial sponsors.

Main Methods:

Centralization of medical imaging data management.
Implementation of relational databases for data storage and retrieval.
Establishment of electronic workflows for standardized processes.

Main Results:

Improved consistency and accuracy of imaging data.
Reduced number of imaging protocol deviations.
Avoidance of delays in data transfer to sponsors.

Conclusions:

Centralized clinical trial imaging data management enhances data quality and efficiency.
Standardized electronic workflows and relational databases are key to successful implementation.
This approach ensures reliable imaging data crucial for clinical trial success.