Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Regulation of Food Intake01:30

Regulation of Food Intake

2.9K
Short-term regulation of food intake primarily involves neural signals from the gastrointestinal (GI) tract, blood nutrient levels, and GI tract hormones. Communication between the gut and brain via vagal nerve fibers plays a significant role in evaluating the contents of the gut. Clinical studies have shown that protein ingestion produces a more prolonged response in these nerve fibers compared to an equivalent amount of glucose. Additionally, the activation of stretch receptors caused by GI...
2.9K
Microorganisms in Agriculture and Food industry01:27

Microorganisms in Agriculture and Food industry

1.5K
Microorganisms play a crucial role in agriculture and the food industry, contributing to soil fertility, crop protection, and food production. Their functions range from nitrogen fixation and biopesticide production to fermentation and food preservation, making them indispensable to sustainable farming and food safety.Role in AgricultureNitrogen-fixing bacteria, such as Rhizobium (symbiotic) and Azotobacter (free-living), convert atmospheric nitrogen into ammonia through biological nitrogen...
1.5K
Pharmacokinetics: Drug–Food and Drug–Viral Interactions01:26

Pharmacokinetics: Drug–Food and Drug–Viral Interactions

247
A drug interaction occurs when the concurrent use of another drug, food, or an external substance alters the pharmacological activity of a drug. This interaction can modify the action of the original drug, affecting its effectiveness and safety.Drug–food interactions are significant as they impact drug absorption, metabolism, and excretion. For example, grapefruit juice is a well-known disruptor of drug metabolism. It inhibits the cytochrome P450 3A4 enzyme, crucial for the metabolism of...
247
Allergic Reactions02:06

Allergic Reactions

32.4K
Overview
32.4K
Neural Regulation01:37

Neural Regulation

43.4K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
43.4K
What is Monogastric Digestion?01:50

What is Monogastric Digestion?

75.3K
The human body contains a monogastric digestive system. In a monogastric digestive system, the stomach only contains one chamber in which it digests food. Several other animal species also have monogastric digestive systems, including pigs, horses, dogs, and birds. This chapter, however, focuses on the human digestive system.
75.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mouse Models of Food Allergies: Where Do They Take Us?

Clinical reviews in allergy & immunology·2026
Same author

Revealing the Diverse Allergenic Protein Repertoire of Six Widely Consumed Crab Species: A Species-Specific Allergen in King Crab.

Allergy·2025
Same author

Fish Allergenicity Ladder and Parvalbumin Epitopes for Predicting Clinical Cross-Reactivity and Reintroduction in Chinese Population.

Allergy·2025
Same author

Functional analysis and modification of anti-lipopolysaccharide factor (ALF) from the freshwater crab Sinopotamon henanense and preparation of a novel ShALF6-2 K-AgNPs complex.

International journal of biological macromolecules·2025
Same author

Development and Evaluation of Real-Time Quantitative PCR Assays for Detection of <i>Phellinus noxius</i> Causing Brown Root Rot Disease.

Plant disease·2024
Same author

Hyaluronic acid/PEO electrospun tube reduces tendon adhesion to levels comparable to native tendons - An in vitro and in vivo study.

International journal of biological macromolecules·2024

Related Experiment Video

Updated: Jan 31, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.6K

Microbiota and Food Allergy.

Shang-An Shu1, Agatha W T Yuen2, Elena Woo1

  • 1Division of Rheumatology/Allergy and Clinical Immunology, School of Medicine, The University of California, 451 Health Sciences Drive, Suite 6510, Davis, California, 95616, USA.

Clinical Reviews in Allergy & Immunology
|December 20, 2018
PubMed
Summary
This summary is machine-generated.

The gut microbiota influences food allergy development. Probiotics show promise for prevention and treatment, but more research is needed on mechanisms and optimal use.

Keywords:
Food antigensHygiene hypothesisIntestinal microbiotaMicrobe-host interactionsProbioticsShort-chain fatty acidsTolerance

More Related Videos

Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.5K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

5.6K

Related Experiment Videos

Last Updated: Jan 31, 2026

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation
04:34

Mouse Body Temperature Measurement Using Infrared Thermometer During Passive Systemic Anaphylaxis and Food Allergy Evaluation

Published on: September 14, 2018

26.6K
Basophil Activation Test for Allergy Diagnosis
07:22

Basophil Activation Test for Allergy Diagnosis

Published on: May 31, 2021

9.5K
Murine Fecal Isolation and Microbiota Transplantation
07:32

Murine Fecal Isolation and Microbiota Transplantation

Published on: May 26, 2023

5.6K

Area of Science:

  • Immunology
  • Microbiology
  • Gastroenterology

Background:

  • The rising incidence of food allergies is linked to alterations in gut microbiota composition and function.
  • Microbiota-host interactions are crucial for immune system regulation, with early-life microbial exposures shaping immune development.
  • Antibiotic use can disrupt gut homeostasis, increasing allergy risk, while microbial metabolites like short-chain fatty acids offer protection.

Purpose of the Study:

  • To review the current understanding of the gut microbiota's role in food allergy.
  • To highlight the potential of probiotics as a preventive and therapeutic strategy for food allergies.
  • To identify gaps in knowledge regarding the mechanisms of microbiota-host interactions and probiotic efficacy.

Main Methods:

  • Literature review of emerging evidence on gut microbiota and food allergy.
  • Analysis of studies on early-life microbial exposures, antibiotic effects, and microbial metabolites.
  • Examination of preclinical and clinical data on probiotic interventions for food allergies.

Main Results:

  • Gut microbiota composition and function are associated with food allergy prevalence.
  • Factors like delivery mode, breastfeeding, and antibiotic use significantly impact gut microbiota and allergy risk.
  • Probiotics, including specific commensals like Clostridia, have demonstrated potential in preventing or resolving allergic symptoms in models and trials.

Conclusions:

  • The gut microbiota plays a significant role in the development and regulation of food allergies.
  • Probiotics represent a promising avenue for food allergy management, though their anti-allergic mechanisms require further elucidation.
  • Future research should focus on understanding microbiota-host interactions, gut immunity, and establishing standardized probiotic treatment protocols for food allergies.