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Related Experiment Video

Updated: Jan 31, 2026

Layer Microdissection of Tricuspid Valve Leaflets for Biaxial Mechanical Characterization and Microstructural Quantification
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Trans-apical systemic tricuspid valve-in-ring replacement.

Joanna Ghobrial1, Brian Reemtsen2, Daniel S Levi3

  • 1Division of Cardiology, Heart and Vascular Institute, Cleveland Clinic Foundation, Cleveland, Ohio.

Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions
|December 20, 2018
PubMed
Summary
This summary is machine-generated.

Transcatheter valve replacement is a safe option for high-risk patients with congenital heart disease. This case highlights successful transcatheter tricuspid valve replacement for severe regurgitation after Mustard repair.

Keywords:
BALACONAPVLLSHDI

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Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Congenital Heart Disease

Background:

  • Transcatheter valve replacement (TVR) is an emerging alternative to conventional surgery for congenital heart disease patients, particularly those with high surgical risk.
  • Severe tricuspid valve (TV) regurgitation is a significant cause of morbidity and mortality in patients with D-transposition of the great arteries (d-TGA) following Senning or Mustard repair.
  • Systemic TV replacement is a viable option for patients without severe systemic ventricular dysfunction.

Observation:

  • A patient with d-TGA status post Mustard repair and TV ring placement presented with severe systemic TV regurgitation.
  • The patient was deemed at high surgical risk for traditional open-heart surgery.

Findings:

  • Successful transcatheter valve replacement of the systemic tricuspid valve was performed via a trans-apical approach.
  • An Edwards Sapien XT valve was utilized for the transcatheter procedure.

Implications:

  • Transcatheter valve replacement offers a minimally invasive and effective solution for complex congenital heart disease cases with severe tricuspid regurgitation.
  • This approach provides a crucial treatment option for high-risk patients who may not be candidates for conventional surgical repair or replacement.
  • Further research into transcatheter techniques for systemic valve disease in d-TGA patients is warranted.