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Updated: Jan 31, 2026

Motor Dual-Tasks for Gait Analysis and Evaluation in Post-Stroke Patients
Published on: March 11, 2021
Power Spectral Density Analysis of Long-Term Motor Recovery in Patients With Subacute Stroke
Yu-Sun Min1,2,3, Jang Woo Park4, Kyung Eun Jang1
11 Kyungpook National University, Daegu, Korea.
Background:
Prognostic measures of long-term motor recovery are important in patients with stroke presenting with severe hemiplegia.
Objective:
We aimed to investigate whether initial power spectral density (PSD) analysis of resting-state functional magnetic resonance (fMRI) data can provide a sensitive prognostic predictor in patients with subacute stroke with severe hand disability.
Methods:
Twelve patients with good recovery, 14 patients with poor recovery, and 12 healthy subjects were included. PSD analysis was performed using resting-state fMRI data. Contralesional and ipsilesional PSD in the motor cortex were measured. Pearson correlation analysis was performed to assess a possible association between the difference in ipsilesional versus contralesional PSD and motor outcomes. A receiver operating characteristic (ROC) curve was constructed to estimate the discriminative value of the difference between the ipsilesional PSD and the contralesional PSD for good versus poor recovery.
Results:
There were no differences in PSD between the contralesional and ipsilesional hemispheres in the good recovery group ( P = .77). In contrast, there were significant differences in PSD between the 2 hemispheres in the poor recovery group ( P = .07). The difference in PSD between the 2 hemispheres had a positive correlation with post Brunnstrom stage scores. ROC analysis showed that the difference in PSD between the 2 hemispheres was sensitive in discriminating good versus poor recovery.
Conclusion:
The present study suggests that PSD in the motor cortex may be a sensitive predictor of late-onset motor recovery following stroke.
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