Clampless cardioplegia: an alternative to conventional cardioplegia administration

Sean Clingan1, James Reagor1

  • 1Department of Cardiovascular Perfusion, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

Perfusion
|December 20, 2018
PubMed

Insights

Clampless cardioplegia offers a vital alternative for myocardial protection in cardiac surgery when aortic cross-clamping is not feasible. This approach ensures a quiescent heart and bloodless field, with no observed cardiac functional changes in four patients.

Area of Science:

  • Cardiovascular Surgery
  • Cardiac Anesthesia
  • Cardiothoracic Medicine

Background:

  • Myocardial protection is critical during cardiac surgery.
  • Standard cardioplegia delivery is challenging in certain patient populations.
  • Alternative methods are needed for patients where aortic cross-clamping is not possible.

Purpose of the Study:

  • To develop a policy and protocol for clampless or systemic cardioplegia.
  • To evaluate the feasibility and safety of this technique in specific surgical scenarios.
  • To report on the peri-operative outcomes of patients receiving clampless cardioplegia.

Main Methods:

  • Development of a specific protocol for clampless cardioplegia administration.
  • Application of the protocol in four distinct patient cases.
  • Peri-operative monitoring including post-operative echocardiography.

Main Results:

  • Successful implementation of clampless cardioplegia in four patients.
  • No significant changes in cardiac function were detected by post-operative echocardiograms.
  • No peri-operative complications were reported in the treated patients.

Conclusions:

  • Clampless cardioplegia is a viable alternative for myocardial protection when standard methods are contraindicated.
  • This protocol provides a safe and effective option for achieving a bloodless field and quiescent heart.
  • Further studies may explore broader applications and long-term outcomes.

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