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Published on: September 28, 2022
Pediatric oncologic emergencies: Clinical and imaging review for pediatricians
Atsuhiko Handa1,2, Taiki Nozaki1, Akari Makidono1,3
1Department of Radiology, St Luke's International Hospital, Tokyo, Japan.
Insights
Pediatric cancer patients face life-threatening emergencies from cancer or its treatment. Prompt diagnosis using radiology is crucial for timely intervention and improved outcomes in these critical oncologic emergencies.
Area of Science:
- Pediatric Oncology
- Emergency Medicine
- Diagnostic Radiology
Background:
- Children with cancer have a high risk of life-threatening emergencies.
- These emergencies arise from the malignancy or its treatment, necessitating rapid assessment and intervention.
- Cardiothoracic and abdominal emergencies are common, impacting morbidity and mortality.
Purpose of the Study:
- To review clinical features and imaging findings of oncologic emergencies in pediatric patients.
- To highlight the vital role of radiology in diagnosing these critical conditions.
- To emphasize collaborative diagnosis and treatment strategies among pediatric specialists.
Main Methods:
- Review of clinical presentations of pediatric oncologic emergencies.
- Analysis of radiological imaging features for various cardiothoracic and abdominal emergencies.
- Inclusion of recently published studies and key radiological images.
Main Results:
- Detailed description of pathologies like pericardial effusion, cardiac tamponade, massive hemoptysis, superior vena cava syndrome, pulmonary embolism, pneumonia, bowel obstruction, intussusception, perforation, tumor rupture, graft-versus-host disease, pancreatitis, neutropenic colitis, and obstructive uropathy.
- Emphasis on the diagnostic utility of radiology in identifying these emergencies.
- Presentation of illustrative radiological images.
Conclusions:
- Radiology is indispensable for the prompt and accurate diagnosis of pediatric oncologic emergencies.
- Multidisciplinary collaboration between pediatricians, surgeons, and radiologists is essential for optimal patient management.
- Early diagnosis and treatment are key to minimizing morbidity and mortality in these high-risk patients.
Abstract:
Children with cancer are at increased risk of life-threatening emergencies, either from the cancer itself or related to the cancer treatment. These conditions need to be assessed and treated as early as possible to minimize morbidity and mortality. Cardiothoracic emergencies encompass a variety of pathologies, including pericardial effusion and cardiac tamponade, massive hemoptysis, superior vena cava syndrome, pulmonary embolism, and pneumonia. Abdominal emergencies include bowel obstruction, intussusception, perforation, tumor rupture, intestinal graft-versus-host disease, acute pancreatitis, neutropenic colitis, and obstructive uropathy. Radiology plays a vital role in the diagnosis of these emergencies. We here review the clinical features and imaging in pediatric patients with oncologic emergencies, including a review of recently published studies. Key radiological images are presented to highlight the radiological approach to diagnosis. Pediatricians, pediatric surgeons, and pediatric radiologists need to work together to arrive at the correct diagnosis and to ensure prompt and appropriate treatment strategies.
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