Self-Healing Supramolecular Hydrogels for Tissue Engineering Applications
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Updated: Jan 31, 2026

Injectable Supramolecular Polymer-Nanoparticle Hydrogels for Cell and Drug Delivery Applications
Published on: February 7, 2021
Laura Saunders1, Peter X Ma1,2,3,4
1Macromolecular Science and Engineering Center, University of Michigan, Ann Arbor, 48109, MI, USA.
Abstract:
Self-healing supramolecular hydrogels have emerged as a novel class of biomaterials that combine hydrogels with supramolecular chemistry to develop highly functional biomaterials with advantages including native tissue mimicry, biocompatibility, and injectability. These properties are endowed by the reversibly cross-linked polymer network of the hydrogel. These hydrogels have great potential for realizing yet to be clinically translated tissue engineering therapies. This review presents methods of self-healing supramolecular hydrogel formation and their uses in tissue engineering as well as future perspectives.
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