Pharmacological treatment of early Parkinson's disease

Initiation of medical treatment of early stage of Parkinson's disease (PD) is consisted of pharmacological and no-pharmacological treatment. When and which drug is rationale for initial treatment is still controversial except young-onset PD patient. Initial drug should be decided according to patient state, age of onset and present, severity and cognition. Dopamine agonist is rationale for young-onset PD patient at early stage. Disease modify therapy is not established.