Related Experiment Video
Updated: Jan 31, 2026

Bioluminescence and Near-infrared Imaging of Optic Neuritis and Brain Inflammation in the EAE Model of Multiple Sclerosis in Mice
Published on: March 1, 2017
The Most/Common Eye Manifestation in Multiple Sclerosis: Optic Neuritis
Abstract:
Multiple sclerosis (MS) is an immune-mediated dis- ease of the central nervous system. It is diagnosed most often in persons between the ages of 20 and 40 years. The effects of this disease can be numerous, and for some individuals it can be very disabling. Fortunately, there arenow many disease-modifying medications to treat persons who have a relapsing form of MS. Visual symptoms are among the many symptoms of MS. The most common visual condition is optic neuritis (ON), occurring in up to 50% of persons as the first symptom of MS (Abou Zeid & Bhetti, 2008; Jacobs et al., 2000; Kappos et al., 2006). This article highlights symptoms, assessment, diagnosis, treatment, and outcomes of ON. Implications for collaboration across spe- cialties are also discussed.
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