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Updated: Jan 31, 2026

Novel Photoacoustic Microscopy and Optical Coherence Tomography Dual-modality Chorioretinal Imaging in Living Rabbit Eyes

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[Cornea Imaging by Optical Coherence Tomography - Historical Aspects and Most Recent Technical Developments].

René M Werkmeister^1,2, Hannes Stegmann^1,2, Valentin Aranha Dos Santos¹

¹Zentrum für Medizinische Physik und Biomedizinische Technik, Medizinische Universität Wien, Österreich.

Klinische Monatsblatter Fur Augenheilkunde

|December 20, 2018

Summary

Optical coherence tomography (OCT) has evolved from retinal imaging to revolutionize anterior eye segment assessment. This technology offers high-resolution visualization and precise measurements for diagnosing and monitoring corneal diseases.

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Area of Science:

Ophthalmology
Biomedical Optics

Background:

Optical coherence tomography (OCT) initially focused on retinal imaging.
Recent advancements have led to specialized OCT systems for anterior eye segment assessment.

Purpose of the Study:

To highlight the evolution and applications of OCT in ophthalmology.
To detail the capabilities of OCT in examining anterior eye structures.

Main Methods:

OCT utilizes back-scattered and back-reflected light for tissue imaging.
Systems are developed for precise measurement of corneal layers and chamber angles.
Ultrahigh resolution OCT provides near-histological visualization of corneal morphology.

Main Results:

OCT enables detailed examination of anterior eye segment structures.
Precise measurements of cornea and chamber angle are achievable.
Ultrahigh resolution OCT visualizes corneal morphology with exceptional detail.

Conclusions:

OCT has become indispensable for differential diagnosis and follow-up of corneal diseases.
Advancements in acquisition speed enhance OCT's clinical utility.
OCT offers potential for new insights into corneal pathophysiology.