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Development and Assessment of Intracellular Infection Models for Staphylococcus aureus
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Case of ruptured Staphylococcus aureus aortitis: presentation and management
Stephani C Wang1, Mohamed Tageldin2, Drinnon O Hand1
1Internal Medicine, Albany Medical Center, Albany, New York, USA.
BMJ Case Reports
|December 21, 2018
Summary
Infectious aortitis, though rare with Staphylococcus aureus, can rapidly progress to fatal aortic rupture. This case highlights successful staged repair and antibiotic treatment for methicillin-sensitive SA aortitis with rupture.
Area of Science:
- Cardiovascular Surgery
- Infectious Diseases
- Vascular Medicine
Background:
- Infectious aortitis, particularly with Staphylococcus aureus (SA), presents a high mortality risk due to potential aortic rupture.
- Early diagnosis and prompt, comprehensive management are crucial for improving outcomes in patients with infectious aortitis.
Observation:
- A 65-year-old male presented with methicillin-sensitive Staphylococcus aureus (SA) aortitis, which rapidly progressed to aortic rupture.
- The patient's condition necessitated immediate and complex surgical intervention.
Findings:
- Successful treatment was achieved through a staged vascular repair approach.
- Long-term antibiotic therapy was integral to the patient's recovery and management.
Implications:
- This case underscores the importance of recognizing SA as a potential pathogen in infectious aortitis, even when methicillin-sensitive.
- Aggressive, multi-modal treatment including staged surgery and prolonged antibiotics can be effective in managing life-threatening aortic rupture secondary to infectious aortitis.
- Further research into optimal antibiotic durations and surgical strategies for SA aortitis is warranted.
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