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Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Citrobacter freundii sepsis in an immunosuppressed patient with pemphigus vulgaris
Martina Ferranti1, Giulia Tadiotto Cicogna1, Andrea Sattin2
1Unit of Dermatology, University of Padua, Padua, Italy.
Abstract:
Pemphigus vulgaris is an autoimmune bullous disease that involves the skin and mucous membranes. Current therapies aim to decrease antibody production by means of the use of systemic corticosteroids, immunosuppressive agents and, recently, rituximab, an anti-CD20 monoclonal antibody. However, the chronic immune suppression could entail complications, like infections and secondary malignancies. We describe a case of a patient with pemphigus who developed a sepsis due to Citrobacter freundii infection.
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