The prognostic value of quantitative analysis in the endometrial carcinoma

The epithelial and stromal components in 146 adenocarcinomas, adenocanthomas and adenosquamous carcinomas of the endometrium were quantified morphometrically on Feulgen-stained tissue sections. The classification of the tumors was based on the criteria of World Health Organization and International Federation of Gynecology and Obstetrics. As expected, the survival percentage of the patients fell with the advancing clinical stage and histological grade. The ratio of the epithelial cells to the stromal ones proved to be a good prognostic indicator and may be useful in identification of cases with the most favorable prognosis among grade 1 tumors. A high mitotic activity predicted poor prognosis to the patient although statistical significance was not achieved.