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Updated: Jan 31, 2026

Perturbations of Circulating miRNAs in Irritable Bowel Syndrome Detected Using a Multiplexed High-throughput Gene Expression Platform
Published on: November 30, 2016
Efficacy of Mirtazapine on Irritable Bowel Syndrome with Anxiety and Depression: A Case Study
Fumiaki Akama1, Katsunaka Mikami1, Natsuru Watanabe1
1Department of Psychiatry, Tokai University School of Medicine.
Abstract:
Irritable bowel syndrome (IBS) is a disease in which gastrointestinal symptoms-primarily abdominal pain or discomfort and abnormal bowel movements persist chronically. For patients with IBS, mental illness, especially depression and/or anxiety, leads to a further lower quality of life. The purpose of this case study was to investigate the effects of mirtazapine (MIR) on mental health and IBS symptoms in a case of IBS accompanied by anxiety and a depressive state. This case report suggests that MIR is efficacious for the treatment of IBS with predominant diarrhea accompanied by depression and anxiety.
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