Related Experiment Video
Updated: Jan 31, 2026
06:35
An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
Published on: February 8, 2019
7.6K
Giant Cell Arteritis with Generalized Granuloma Annulare
Yuichi Torisu1, Yoshiro Horai2,3, Tohru Michitsuji1,4
1Department of General Internal Medicine, National Hospital Organization Nagasaki Medical Center, Japan.
Internal Medicine (Tokyo, Japan)
|December 21, 2018
Summary
Generalized granuloma annulare (GGA) can lead to giant cell arteritis (GCA). Steroid treatment effectively managed both conditions in an 80-year-old patient, highlighting a potential complication of GGA.
Area of Science:
- Dermatology
- Rheumatology
- Pathology
Background:
- Generalized granuloma annulare (GGA) is a rare inflammatory skin condition.
- Giant cell arteritis (GCA) is a systemic vasculitis affecting large arteries.
Observation:
- An 80-year-old male patient presented with generalized granuloma annulare.
- The patient subsequently developed symptoms suggestive of giant cell arteritis.
Findings:
- Concomitant occurrence of GGA and GCA was observed in this case.
- Histological similarities between GGA and GCA suggest a potential shared pathogenesis.
- Steroid therapy demonstrated efficacy in treating both conditions concurrently.
Implications:
- Clinicians should consider the possibility of GCA in patients with GGA, especially those exhibiting characteristic symptoms like headache and visual disturbances.
- Recognizing this association may lead to earlier diagnosis and treatment of GCA in GGA patients.
- Further research into the underlying mechanisms connecting GGA and GCA is warranted.
Related Concept Videos
01:22Generalized Hooke's Law
2.7K
The generalized Hooke's Law is a broadened version of Hooke's Law, which extends to all types of stress and in every direction. Consider an isotropic material shaped into a cube subjected to multiaxial loading. In this scenario, normal stresses are exerted along the three coordinate axes. As a result of these stresses, the cubic shape deforms into a rectangular parallelepiped. Despite this deformation, the new shape maintains equal sides, and there is a normal strain in the direction of the...
2.7K
01:30Generalized Anxiety Disorder
699
Generalized Anxiety Disorder (GAD) is a chronic condition characterized by excessive and uncontrollable worry that persists for at least six months, significantly interfering with daily functioning. Unlike situational anxiety, which arises in response to specific stressors, GAD often occurs without a clear cause. Individuals may experience disproportionate worry about work, health, or relationships. For instance, a person might continuously fear poor health despite normal medical evaluations or...
699
01:20Social Foundations of Self II: The Generalized Other
260
According to George Herbert Mead, as children progress beyond the game stage, they develop a more comprehensive understanding of societal rules and norms. This cognitive and social development enables them to internalize the expectations of the broader community, refining their ability to regulate behavior.Consistent participation in organized activities is crucial in helping children recognize that their actions are not isolated but contribute to a more significant, interconnected group...
260
01:24Generalization, Discrimination, and Extinction
1.4K
Generalization, discrimination, and extinction are key concepts in operant conditioning that influence how behaviors are learned and maintained.
Generalization occurs when a behavior reinforced in one context is performed in similar situations. For instance, a student who studies diligently for calculus and receives excellent grades might apply the same study habits to psychology and history, expecting similar results. Generalization shows how learning in one setting can influence behavior in...
Generalization occurs when a behavior reinforced in one context is performed in similar situations. For instance, a student who studies diligently for calculus and receives excellent grades might apply the same study habits to psychology and history, expecting similar results. Generalization shows how learning in one setting can influence behavior in...
1.4K
01:07What are Cells?
199.3K
Cells are the smallest and basic units of life, whether it is a single cell that forms the entire organism, e.g., in a bacterium or trillions of them, e.g., in humans. No matter what organism a cell is a part of, they share specific characteristics.
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
Basic Characteristics of Cells
A living cell has a plasma membrane, a bilayer of lipids that separates the aqueous solution inside the cell called the cytoplasm from the outside environment.
Furthermore, a living cell possesses genetic information...
199.3K
02:03What is Cell Signaling?
130.4K
Despite the protective membrane that separates a cell from the environment, cells need the ability to detect and respond to environmental changes. Additionally, cells often need to communicate with one another. Unicellular and multicellular organisms use a variety of cell signaling mechanisms to communicate to respond to the environment.
130.4K