Related Experiment Video
Updated: Jan 31, 2026
Leprdb Mouse Model of Type 2 Diabetes: Pancreatic Islet Isolation and Live-cell 2-Photon Imaging Of Intact Islets
Published on: May 11, 2015
Development of a prediction model for pancreatic cancer in patients with type 2 diabetes using logistic regression
Meng Hsuen Hsieh1, Li-Min Sun2, Cheng-Li Lin3,4
1Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, CA, USA.
Objectives:
Patients with type 2 diabetes (T2DM) are suggested to have a higher risk of developing pancreatic cancer. We used two models to predict pancreatic cancer risk among patients with T2DM.
Methods:
The original data used for this investigation were retrieved from the National Health Insurance Research Database of Taiwan. The prediction models included the available possible risk factors for pancreatic cancer. The data were split into training and test sets: 97.5% of the data were used as the training set and 2.5% of the data were used as the test set. Logistic regression (LR) and artificial neural network (ANN) models were implemented using Python (Version 3.7.0). The F 1, precision, and recall were compared between the LR and the ANN models. The areas under the receiver operating characteristic (ROC) curves of the prediction models were also compared.
Results:
The metrics used in this study indicated that the LR model more accurately predicted pancreatic cancer than the ANN model. For the LR model, the area under the ROC curve in the prediction of pancreatic cancer was 0.727, indicating a good fit.
Conclusion:
Using this LR model, our results suggested that we could appropriately predict pancreatic cancer risk in patients with T2DM in Taiwan.
Related Concept Videos
01:22Diabetes Mellitus: Type 2 and Gestational
01:52Regression Toward the Mean
02:27Predicting Products: SN1 vs. SN2
With increased substitution on the alkyl halide,...
01:19Psychoneuroimmunology: Diabetes and Cancer
02:26Protein Networks
These interactions can be represented through maps depicting protein-protein interaction networks, represented as nodes and edges. Nodes are circles that are representative of a protein,...
01:22Diabetes Mellitus: Overview and Type I Subtype
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks and destroys the insulin-producing beta cells in the pancreas. As a result, the body is unable to produce sufficient insulin, and individuals with...