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Immune thrombocytopenia: improving quality of life and patient outcomes

Patrick Trotter1,2, Quentin A Hill3

  • 1Department of Surgery, University of Cambridge, Cambridge, UK.

Patient Related Outcome Measures
|December 21, 2018
PubMed

Immune thrombocytopenia (ITP) is an immune-mediated disorder characterized by a reduced platelet count and patients may develop bruising or mucosal bleeding. Since 2003, generic health-related quality of life (HRQoL) measures have been applied and ITP-specific measures developed, alongside trials of novel therapeutic agents. These have identified significant morbidity in patients with ITP, including fatigue, fear of bleeding and a negative impact on role, social and work activities. This review critically evaluates HRQoL data in adults and children with ITP. It also considers the impact of treatment and how patient-reported outcomes might be applied to care to optimize patients' quality of life.

Keywords:
ITP-PAQKITSF-36bleedingdepressioneltrombopagfatigueimmune thrombocytopeniaquality of liferomiplostim

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