Related Experiment Video
Updated: Jan 31, 2026

A Protocol for Roux-en-Y Gastric Bypass in Rats using Linear Staplers
Published on: August 21, 2021
Alternative Method of Mesenteric Defect Closure after Roux-en-Y Gastric Bypass
1Department of Surgery, Section of Advanced Laparoscopic and Bariatric Surgery, MedStar Washington Hospital Center, 106 Irving Street NW, Physicians Office Building South Tower Suite 301, Washington, DC, 20010, USA.
Background:
Roux-en-Y gastric bypass is the gold standard for weight loss surgery. This procedure creates two to three mesenteric defects, depending on ante-colic versus retro-colic technique. Current literature supports mesenteric defect closure, but there is no consensus on how to best close these defects. Described options include running separate suture lines for each defect, or employing endoscopic staplers for defect closure.
Methods:
This is a video/dynamic manuscript on operative technique.
Results:
We describe an alternative technique that does not require an extra laparoscopic instrument and is more efficient than traditional suture lines due to less suturing.
Conclusions:
The technique maintains low gastric bypass complication rates by closing mesenteric defects, while keeping intra-operative costs low, and minimizing time spent on the defect closures.
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