Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Eosinophilic nonallergic rhinitis.

M F Mullarkey1

  • 1Virginia Mason Clinic, Seattle, Wash.

The Journal of Allergy and Clinical Immunology
|November 1, 1988
PubMed
Summary
This summary is machine-generated.

Eosinophilic nonallergic rhinitis, characterized by nasal eosinophils, responds well to treatments. This condition showed a statistically better response to antihistamines and topical corticosteroids than allergic rhinitis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Methotrexate revisited.

Chest·1997
Same author

Human cutaneous allergic late-phase response is inhibited by soluble IL-1 receptor.

Journal of immunology (Baltimore, Md. : 1950)·1994
Same author

Use of methotrexate in the treatment of steroid-dependent adolescent asthmatics.

Annals of allergy·1991
Same author

Methotrexate and asthma.

The Journal of allergy and clinical immunology·1991
Same author

Long-term methotrexate treatment in corticosteroid-dependent asthma.

Annals of internal medicine·1990
Same author

Methotrexate in the treatment of corticosteroid-dependent asthma. A double-blind crossover study.

The New England journal of medicine·1988

Area of Science:

  • Otolaryngology
  • Allergy and Immunology

Background:

  • Eosinophilic nonallergic rhinitis is a significant subtype of nonallergic rhinitis.
  • It is defined by eosinophils in nasal secretions, absence of allergen triggers, and negative allergy skin tests.
  • This condition is frequently linked with nasal polyps and shows high sensitivity to corticosteroids.

Purpose of the Study:

  • To differentiate and characterize allergic and nonallergic rhinitis subtypes.
  • To evaluate treatment responses in patients with eosinophilic nonallergic rhinitis.

Main Methods:

  • Patients with rhinitis were categorized using diagnostic criteria including history, nasal mucosa status, skin tests, and IgE levels.
  • A study involved 142 rhinitis patients, classifying them into allergic, probable allergic, vasomotor, and eosinophilic nonallergic rhinitis groups.

Related Experiment Videos

  • Treatment response rates to antihistamines and topical flunisolide were assessed.

    • Main Results:

    • The study identified 34% allergic rhinitis, 15% probable allergic rhinitis, 37% vasomotor rhinitis, and 15% eosinophilic nonallergic rhinitis.
    • Eighty-three percent of eosinophilic nonallergic rhinitis patients responded to antihistamines, and 93% responded to topical flunisolide, with an overall 90% response rate.
    • Patients with eosinophilic nonallergic rhinitis demonstrated a statistically superior response to these medications compared to those with allergic rhinitis.

    Conclusions:

    • Eosinophilic nonallergic rhinitis is a distinct rhinitis subtype.
    • Effective treatment options for eosinophilic nonallergic rhinitis include antihistamines and topical corticosteroids.
    • These treatments show superior efficacy in eosinophilic nonallergic rhinitis compared to allergic rhinitis.