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Updated: Jan 31, 2026

Rapid Point-of-Care Assay of Enoxaparin Anticoagulant Efficacy in Whole Blood
Published on: October 12, 2012
[Frameworks for responsible anticoagulation care: a contribution to a collective view]
Richard J Folkeringa1,2, G J Geersing3, Hugo Ten Cate4
1Medisch Centrum Leeuwarden, afd. Cardiologie.
Vitamin K antagonists (VKAs) and direct oral anticoagulants (DOACs) are key anticoagulation therapies. This study explores frameworks for responsible anticoagulation care, addressing coordination and patient support challenges.
Area of Science:
- Pharmacology and Therapeutics
- Patient Care Management
- Health Policy
Background:
- Vitamin K antagonists (VKAs) were historically the primary anticoagulation method for atrial fibrillation and venous thromboembolisms.
- Care coordination faced challenges, particularly regarding interinstitutional continuity of care, leading to national standards (LSKA, LESA).
- The rise of direct oral anticoagulants (DOACs) has introduced new complexities in anticoagulation management and patient/caregiver support.
Purpose of the Study:
- To outline frameworks for responsible anticoagulation care in the evolving landscape of anticoagulant therapies.
- To address uncertainties in treatment coordination and follow-up for patients on anticoagulation.
- To provide guidance on managing the transition from VKAs to DOACs and ensuring continuous patient support.
Main Methods:
- Review of current anticoagulation care standards and practices.
- Analysis of challenges in coordinating care involving various healthcare providers.
- Examination of issues related to patient and caregiver support, including information accessibility and treatment switching.
Main Results:
- Existing initiatives like LSKA and LESA aim to improve anticoagulation care continuity.
- The increasing adoption of DOACs presents new challenges in treatment coordination and requires updated care frameworks.
- Clear guidelines are needed for follow-up organization, answering patient queries, and managing VKA to DOAC transitions.
Conclusions:
- Responsible anticoagulation care necessitates robust frameworks addressing coordination, follow-up, and communication.
- Adapting to the widespread use of DOACs is crucial for ensuring safe and effective anticoagulation management.
- Enhanced support systems are vital for patients and caregivers navigating complex anticoagulation therapies.
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