Related Experiment Video
Updated: Jan 31, 2026

Z-Scores for Assessing Ovarian Reserve in Young Patients Undergoing Fertility Preservation
Published on: October 25, 2024
Society of Thoracic Surgeons Risk Score and EuroSCORE-2 Appropriately Assess 30-Day Postoperative Mortality in the
Nadia Bouabdallaoui1, Susanna R Stevens2, Torsten Doenst3
1Departments of Medicine, ontreal Heart Institute, University of Montreal, Canada (N.B., J.L.R.).
Insights
The Society of Thoracic Surgeons (STS) and EuroSCORE-2 (ES2) risk scores effectively assess 30-day mortality after coronary artery bypass grafting in patients with left ventricular dysfunction, though STS scores tend to underestimate risk.
Area of Science:
- Cardiovascular Surgery
- Cardiac Surgery Risk Assessment
- Medical Device Evaluation
Background:
- The STICH trial confirmed survival benefits of coronary artery bypass grafting (CABG) for ischemic cardiomyopathy.
- Accurate risk assessment is crucial for CABG in patients with left ventricular dysfunction (LVD).
- Limited data exist on the performance of STS and EuroSCORE-2 (ES2) in LVD patients undergoing CABG.
Purpose of the Study:
- To evaluate the accuracy of the Society of Thoracic Surgeons (STS) risk score and EuroSCORE-2 (ES2) in predicting 30-day postoperative mortality.
- To compare the predictive performance of STS and ES2 in patients with left ventricular ejection fraction (LVEF) ≤35% undergoing CABG.
- To assess risk stratification in both a clinical trial (STICH) and a contemporary cohort (CC) of LVD patients.
Main Methods:
- Calculated STS and ES2 scores for 814 STICH patients and 1246 contemporary cohort (CC) patients.
- Analyzed 30-day postoperative mortality rates in both cohorts.
- Assessed the predictive accuracy using C-statistics for STS and ES2 scores.
Main Results:
- Significant variation in 30-day postoperative mortality risk was observed.
- STS scores consistently yielded lower risk estimates than ES2.
- Both scores demonstrated moderately good predictive accuracy (C-statistics ranging from 0.707 to 0.744).
- Contemporary cohort patients had higher STS/ES2 scores but lower mortality than STICH patients, suggesting improved outcomes over time.
Conclusions:
- 30-day postoperative mortality risk in CABG patients with LVD varies considerably.
- Both STS and ES2 scores are effective tools for risk evaluation in this population.
- The STS score tends to underestimate the actual postoperative mortality risk.
Background:
The STICH trial (Surgical Treatment for Ischemic Heart Failure) demonstrated a survival benefit of coronary artery bypass grafting in patients with ischemic cardiomyopathy and left ventricular dysfunction. The Society of Thoracic Surgeons (STS) risk score and the EuroSCORE-2 (ES2) are used for risk assessment in cardiac surgery, with little information available about their accuracy in patients with left ventricular dysfunction. We assessed the ability of the STS score and ES2 to evaluate 30-day postoperative mortality risk in STICH and a contemporary cohort (CC) of patients with a left ventricle ejection fraction ≤35% undergoing coronary artery bypass grafting outside of a trial setting.
Methods And Results:
The STS and ES2 scores were calculated for 814 STICH patients and 1246 consecutive patients in a CC. There were marked variations in 30-day postoperative mortality risk from 1 patient to another. The STS scores consistently calculated lower risk scores than ES2 (1.5 versus 2.9 for the CC and 0.9 versus 2.4 for the STICH cohort), and underestimated postoperative mortality risk. The STS and ES2 scores had moderately good C statistics: CC (0.727, 95% CI: 0.650-0.803 for STS, and 0.707, 95% CI: 0.620-0.795 for ES2); STICH (0.744, 95% CI: 0.677-0.812, for STS and 0.736, 95% CI: 0.665-0.808 for ES2). Despite the CC patients having higher STS and ES2 scores than STICH patients, mortality (3.5%) was lower than that of STICH (4.8%), suggesting a possible decrease in postoperative mortality over the past decade.
Conclusions:
The 30-day postoperative mortality risk of coronary artery bypass grafting in patients with left ventricular dysfunction varies markedly. Both the STS and ES2 score are effective in evaluating risk, although the STS score tend to underestimate risk.
Clinical Trial Registration:
URL: https://www.clinicaltrials.gov. Unique identifier: NCT00023595.
More Related Videos
08:19Transthoracic Echocardiography to Assess Post-Resuscitation Left Ventricular Dysfunction After Acute Myocardial Infarction and Cardiac Arrest in Pigs
Published on: July 12, 2022
09:05Transthoracic Speckle Tracking Echocardiography for the Quantitative Assessment of Left Ventricular Myocardial Deformation
Published on: October 20, 2016
Related Concept Videos
Contemporary Psychology
Biopsychology
Biopsychology, also known as biological psychology or behavioral neuroscience, focuses on the biological underpinnings of behavior and mental processes. It...
Thoracic Aorta
Introduction to z Scores
z scores...
Introduction to z Scores
z scores...
z Scores and Area Under the Curve
Design Example: Analyzing Capacity Contours for Flood Risk Assessment