Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hemostatic defect in endoscoped upper gut bleeding.

W H Hall, T Q My, J D Welsh

    Acta Hepato-Gastroenterologica
    |February 1, 1978
    PubMed
    Summary
    This summary is machine-generated.

    Related Concept Videos

    You might also read

    Related Articles

    Articles linked to this work by shared authors, journal, and citation graph.

    Sort by
    Same author

    Examining the associations between self-care practices and psychological distress among nursing students during the COVID-19 pandemic.

    Nurse education today·2021
    Same author

    The Sixth Year Molar.

    The American journal of dental science·2019
    Same author

    Hierarchical organization of the hemostatic response to penetrating injuries in the mouse macrovasculature.

    Journal of thrombosis and haemostasis : JTH·2016
    Same author

    Platelet-targeting thiol reduction sensor detects thiol isomerase activity on activated platelets in mouse and human blood under flow.

    Journal of thrombosis and haemostasis : JTH·2016
    Same author

    Platelet-targeting sensor reveals thrombin gradients within blood clots forming in microfluidic assays and in mouse.

    Journal of thrombosis and haemostasis : JTH·2012
    Same author

    Brucellosis: Specific Therapy in Patients Having Bacteremia.

    Transactions of the American Clinical and Climatological Association·2011
    Same journal

    Regression of amyloidosis secondary to granulomatous ileitis following surgical resection and colchicine administration.

    Acta hepato-gastroenterologica·1979
    Same journal

    Occult blood testing using the guaiac method (haemoccult-test) for detection of tumorous lesions induced with 1,2-dimethyl-hydrazine and acetoxymethyl-methyl-nitrosamine in rats.

    Acta hepato-gastroenterologica·1979
    Same journal

    Metabolism of C-terminal pentapeptide of gastrin in the rat. Part III. The catabolism of the BOC-pentapeptide and its distribution in the organs.

    Acta hepato-gastroenterologica·1979
    Same journal

    Morphometric analysis of the loss of chief and parietal cells after partial gastrectomy for duodenal ulcer.

    Acta hepato-gastroenterologica·1979
    Same journal

    Serum prolactin response to acute and chronic cimetidine administration in man.

    Acta hepato-gastroenterologica·1979
    Same journal

    Effect of low dose secretin and caerulein on pure pancreatic bicarbonate secretion and plasma secretin in man.

    Acta hepato-gastroenterologica·1979
    See all related articles

    This study found no direct link between salicylate ingestion and upper gastrointestinal bleeding. Prolonged bleeding times were associated with liver disease and gastritis, not salicylate use.

    Area of Science:

    • Gastroenterology
    • Pharmacology
    • Hematology

    Background:

    • Salicylate ingestion is common and a potential risk factor for upper gastrointestinal bleeding.
    • The relationship between salicylate use, bleeding time, and gastrointestinal bleeding requires further investigation.

    Purpose of the Study:

    • To evaluate the role of salicylate ingestion in upper gastrointestinal bleeding.
    • To determine if salicylate levels or ingestion history correlate with prolonged bleeding times in patients undergoing endoscopy.

    Main Methods:

    • Prospective observational study involving patients undergoing diagnostic endoscopy.
    • Collected blood for salicylate levels, performed Duke bleeding time, and obtained detailed drug histories.
    • Compared bleeding times and salicylate data between patients with gastrointestinal bleeding and controls.

    Related Experiment Videos

    Main Results:

    • Prolonged bleeding time occurred in 21/81 patients, compared to 1/22 controls.
    • Prolonged bleeding time strongly correlated with liver disease, alcohol history, and severe gastritis.
    • No correlation was found between prolonged bleeding time and plasma salicylate levels or ingestion history.

    Conclusions:

    • Salicylate ingestion did not appear to be a significant factor in upper gastrointestinal bleeding in this cohort.
    • Liver disease and severe gastritis are associated with prolonged bleeding times, independent of salicylate use.