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Related Experiment Video

Updated: Jan 31, 2026

Deep Vascular Imaging in the Eye with Flow-Enhanced Ultrasound
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Motion Artifacts and Correction in Multipulse High-Frame Rate Contrast-Enhanced Ultrasound.

A Stanziola, M Toulemonde, Y Li

    IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
    |December 21, 2018
    PubMed
    Summary
    This summary is machine-generated.

    Motion significantly degrades high-frame-rate contrast-enhanced ultrasound (HFR CEUS) imaging, especially in deep tissues. Motion correction before compounding substantially reduces artifacts, improving image quality for cardiac applications.

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    Area of Science:

    • Medical imaging
    • Ultrasound technology
    • Biomedical engineering

    Background:

    • High-frame-rate ultrasound (HFR US) and contrast-enhanced ultrasound (CEUS) utilize multipulse transmissions for enhanced image quality.
    • Multipulse techniques are susceptible to motion-induced degradation, particularly when combined with coherent compounding and CEUS.

    Purpose of the Study:

    • To investigate the impact of motion on HFR CEUS intensity in deep tissue imaging.
    • To evaluate the effectiveness of motion correction in mitigating artifacts in cardiac HFR CEUS.

    Main Methods:

    • Simulations of HFR CEUS with varying flow directions and velocities.
    • In vivo contrast echocardiography (CE) in cardiac imaging.
    • Analysis of image intensity reduction and signal-to-noise ratio.

    Main Results:

    • Simulations revealed higher motion artifacts with axial flow compared to lateral flow.
    • A 35 cm/s motion caused a 28.5 dB intensity decrease, with compounding contributing up to 18.7 dB.
    • In vivo cardiac HFR CE showed intensity reductions of 10.4 dB due to myocardial and blood velocities.

    Conclusions:

    • Motion artifacts significantly degrade HFR CEUS, especially in cardiac applications with high velocities.
    • Performing motion correction prior to pulse inversion compounding effectively reduces motion artifacts.
    • Motion correction improves signal-to-noise ratio and contrast in HFR CEUS imaging.