Fluidized bed bioreactor for multiple environmental engineering solutions
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Updated: Jan 31, 2026

Engineering Biological-Based Vascular Grafts Using a Pulsatile Bioreactor
Published on: June 14, 2011
Bestami Özkaya1, Anna H Kaksonen2, Erkan Sahinkaya3
1Tampere University, Faculty of Engineering and Natural Sciences, Laboratory of Chemistry and Bioengineering, P.O. Box 541, FI-33101, Tampere, Finland; Yıldız Technical University, Department of Environmental Engineering, Davutpasa, Istanbul, Turkey.
Abstract:
Fluidized bed bioreactors (FBR) are characterized by two-phase mixture of fluid and solid, in which the bed of solid particles is fluidized by means of downward or upward recirculation stream. FBRs are widely used for multiple environmental engineering solutions, such as wastewater treatment, as well as some industrial applications. FBR offers many benefits such as compact bioreactor size due to short hydraulic retention time, long biomass retention on the carrier, high conversion rates due to fully mixed conditions and consequently high mass transfer rates, no channelling of flow, dilution of influent concentrations due to recycle flow, suitability for enrichment of microbes with low Km values. The disadvantages of FBRs include bioreactor size limitations due to the height-to-diameter ratio, high-energy requirements due to high recycle ratios, and long start-up period for biofilm formation. This paper critically reviews some of the key studies on biomass enrichment via immobilisation of low growth yield microorganisms, high-rates via fully mixed conditions, technical developments in FBRs and ways of overcoming toxic effects via solution recycling. This technology has many potential new uses as well as hydrodynamic characteristics, which enable high-rate environmental engineering and industrial applications.
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