Tumour lysis syndrome following eribulin for metastatic uterine leiomyosarcoma
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Updated: Jan 31, 2026

Electrochemotherapy of Tumours
Published on: December 15, 2008
Cindy Pabon1, Ashwini K Esnakula2, Karen Daily3
1College of Medicine, University of Florida, Gainesville, Florida, USA.
Abstract:
A middle-aged woman with a history of leiomyosarcoma of the uterus treated with surgery and adjuvant chemotherapy suffered a bulky metastatic recurrence 1 year later. She elected treatment with palliative eribulin, presenting with acute renal failure and electrolyte abnormalities consistent with tumour lysis syndrome on cycle 1 day 8. Despite aggressive supportive care and treatment including intravenous hydration, bicarbonate and rasburicase, she continued to decline, ultimately foregoing haemodialysis in favour of palliative care and passed away in the hospital.
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