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Idiopathic hypereosinophilic syndrome
1Department of Medicine, University of Kansas Medical Center, Kansas City.
Postgraduate Medicine
|December 1, 1988
Abstract:
Idiopathic hypereosinophilic syndrome is a rare but clearly defined cause of peripheral eosinophilia. The cardiovascular and hematopoietic systems are most severely affected. The clinical manifestations are a result of eosinophilic infiltration into tissues, release of eosinophilic products, and induction of a hypercoagulable state. Treatment is aimed at reducing absolute numbers of eosinophils to prevent tissue damage and halt progression of the disease.