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Related Experiment Video

Updated: Jan 31, 2026

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

A 3D System for Culturing Human Articular Chondrocytes in Synovial Fluid

Published on: January 31, 2012

Dopamine levels in human tear fluid.

Niyati Seshagiri Sharma¹, Suraj Kumar Acharya¹, Archana Padmanabhan Nair¹

¹GROW Research Laboratory, Narayana Nethralaya Foundation, Bengaluru, Karnataka, India.

Indian Journal of Ophthalmology

|December 22, 2018

Summary

This summary is machine-generated.

Tear fluid contains detectable dopamine levels, significantly higher than in plasma. This research demonstrates tear fluid

Keywords:

Dopamine ELISA plasma tear fluid

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Bead Based Multiplex Assay for Analysis of Tear Cytokine Profiles

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Area of Science:

Neuroscience
Biochemistry

Background:

Dopamine is a crucial neurotransmitter.
Measuring dopamine levels typically requires invasive methods.

Purpose of the Study:

To quantify dopamine in human tear fluid.
To establish tear fluid as a non-invasive biospecimen for dopamine analysis.

Main Methods:

Collected tear fluid and plasma from 30 healthy individuals.
Utilized direct competitive chemiluminescent enzyme-linked immunosorbent assay (ELISA) for dopamine quantification.

Main Results:

Dopamine was detected in all tested tear fluid samples.
Tear fluid exhibited significantly higher dopamine concentrations (279-470 pg/ml) compared to plasma (97.2 pg/ml).

Conclusions:

Human tear fluid is a viable non-invasive source for dopamine measurement.
Tear fluid analysis offers a novel approach for monitoring dopamine levels.