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Related Concept Videos

Chemical Reactions01:19

Chemical Reactions

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A chemical reaction is a process by which the bonds in the atoms of substances are rearranged to generate new substances. Matter cannot be created or destroyed in a chemical reaction—the same type and number of atoms that make up the reactants are still present in the products. Merely, the rearrangement of chemical bonds produces new compounds.
Chemical Reactions Rearrange Atoms into New Substances
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A balanced chemical equation provides the information of chemical formulas of the reactants and products involved in the chemical change. A reaction’s stoichiometry helps predict how much of the reactant is needed to produce the desired amount of product, or in some cases, how much product will be formed from a specific amount of the reactant.
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All chemical reactions begin with a reactant, the general term for one or more substances entering the reaction. Sodium and chloride ions, for example, are the reactants in the production of table salt. One or more substances produced by a chemical reaction are called the product. Chemical reactions follow the law of conservation of mass, which means that matter cannot be created nor destroyed in a chemical reaction. The components of the reactants—the number of atoms and the...
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Erwin Chargaff’s rules on DNA equivalence paved the way for the discovery of base pairing in DNA. Chargaff’s rules state that in a double-stranded DNA molecule,
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An acid-base reaction is one in which a hydrogen ion, H+, is transferred from one chemical species to another. Such reactions are of central importance to numerous natural and technological processes, ranging from the chemical transformations within cells or lakes and oceans to the industrial-scale production of fertilizers, pharmaceuticals, and other substances essential to the society.
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Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks
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DNA-Based Chemical Reaction Networks.

Fan Li1,2, Mingshu Xiao1, Hao Pei1

  • 1Shanghai Key Laboratory of Green Chemistry and Chemical Processes, School of Chemistry and Molecular Engineering, East China Normal University, 500 Dongchuan Road, 200241, Shanghai, P.R. China.

Chembiochem : a European Journal of Chemical Biology
|December 22, 2018
PubMed
Summary
This summary is machine-generated.

Researchers are developing artificial chemical reaction networks using DNA (D-CRNs) to mimic biological systems. These programmable networks offer new ways to analyze and engineer biochemical processes.

Keywords:
DNADNA recognitionbiotechnologychemical reaction networksstrand-displacement reactions

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Area of Science:

  • Biochemistry
  • Synthetic Biology
  • Molecular Engineering

Background:

  • Complex biological molecular networks control temporal and spatial molecule concentrations.
  • Bottom-up development of artificial chemical reaction networks is gaining traction.
  • DNA-based chemical reaction networks (D-CRNs) offer programmability and directionality.

Purpose of the Study:

  • To review progress in the development of DNA-based chemical reaction networks (D-CRNs).
  • To provide an overview of significant biochemistry applications of D-CRNs.
  • To discuss future research opportunities for D-CRNs in biochemistry.

Main Methods:

  • Utilizing hybridization and strand-displacement reactions for D-CRN construction.
  • Analyzing the programmability and directionality of D-CRNs.
  • Compiling and reviewing recent decades of D-CRN applications in biochemistry.

Main Results:

  • D-CRNs are a promising tool for describing and analyzing (bio)chemical systems.
  • Significant advancements have been made in D-CRN development and application.
  • The review highlights diverse biochemistry applications enabled by D-CRNs.

Conclusions:

  • DNA-based chemical reaction networks represent a powerful platform for biochemical research and engineering.
  • Further research into D-CRNs can unlock new possibilities in understanding and manipulating biological systems.
  • The field is poised for continued growth and innovation in D-CRN applications.